abstract：:Nanodiamond (ND) particles are popular platforms for the immobilization of molecular species. In the present research, enzyme Escherichia coli inorganic pyrophosphatase (PPase) was immobilized on detonation ND through covalent or noncovalent bonding and its enzymatic activity was characterized. Factors affecting adsor...

journal_title：Biointerphases

authors： Rodina EV,Valueva AV,Yakovlev RY,Vorobyeva NN,Kulakova II,Lisichkin GV,Leonidov NB

更新日期：2015-12-21 00:00:00

abstract：:The aim of this research was to assess the influence of mechanical loading on the ability of Zn-free versus Zn-containing amalgams to promote remineralization at the dentin interface. Sound and caries-affected dentin surfaces (CAD) were restored using Zn-free or Zn-containing dental amalgams. Midcoronal dentin surface...

journal_title：Biointerphases

authors： Toledano M,Aguilera FS,Osorio E,López-López MT,Cabello I,Toledano-Osorio M,Osorio R

更新日期：2015-12-19 00:00:00

abstract：:The vascular endothelial cells (EC) extracellular matrix (ECM) on the biomaterial surface can significantly improve the blood compatibility and cell compatibility of the cardiovascular materials. In the present study, two types of micropatterned TiO2 nanotubes surfaces (gronano and toponano) were fabricated on the tit...

journal_title：Biointerphases

authors： Wu J,Li J,Wu F,He Z,Yang P,Huang N

更新日期：2015-12-17 00:00:00

abstract：:Not only bacteria but also fungal pathogens, particularly Candida species, can lead to biofilm infections on biomedical devices. By covalent grafting of the antifungal drug caspofungin, which targets the fungal cell wall, onto solid biomaterials, a surface layer can be created that might be able to provide long-term p...

journal_title：Biointerphases

authors： Griesser SS,Jasieniak M,Coad BR,Griesser HJ

更新日期：2015-12-14 00:00:00

abstract：:Diamond has outstanding bulk properties such as super hardness, chemical inertness, biocompatibility, luminescence, to name just a few. In the nanoworld, in order to exploit these outstanding bulk properties, the surfaces of nanodiamond (ND) particles must be accordingly engineered for specific applications. Modificat...

journal_title：Biointerphases

authors： Shenderova OA,McGuire GE

更新日期：2015-09-05 00:00:00

abstract：:In this work, four triple negative (TN) cell lines, three ER+ and PR+ receptor positive (RP) cell lines, and one ER+, PR+, and HER2+ cell line were chemically distinguished from one another using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and principal component analysis (PCA). PCA scores separation was...

journal_title：Biointerphases

authors： Robinson MA,Graham DJ,Morrish F,Hockenbery D,Gamble LJ

更新日期：2015-06-28 00:00:00

abstract：:The modeling, fabrication, cell loading, and mechanical and in vitro biological testing of biomimetic, interlockable, laser-made, concentric 3D scaffolds are presented. The scaffolds are made by multiphoton polymerization of an organic-inorganic zirconium silicate. Their mechanical properties are theoretically modeled...

journal_title：Biointerphases

authors： Danilevicius P,Rezende RA,Pereira FD,Selimis A,Kasyanov V,Noritomi PY,da Silva JV,Chatzinikolaidou M,Farsari M,Mironov V

更新日期：2015-06-23 00:00:00

abstract：:The use of nanoparticles is one of the fastest expanding fields in industrial as well as in medical applications, owing to their remarkable characteristics. Silver nanoparticles (AgNPs) are among the most-commercialized nanoparticles because of their antibacterial effects. Laser postionization secondary neutral mass s...

journal_title：Biointerphases

authors： Nees R,Pelster A,Körsgen M,Jungnickel H,Luch A,Galla HJ,Arlinghaus HF

更新日期：2015-06-15 00:00:00

abstract：:Titanium dental implants are commonly used for the replacement of lost teeth, but they present a considerable number of failures due to the infection on surrounding tissues. The aim of this paper is the development of a polyethylene glycol-like (PEG-like) coating on the titanium surface by plasma polymerization to obt...

journal_title：Biointerphases

authors： Buxadera-Palomero J,Canal C,Torrent-Camarero S,Garrido B,Javier Gil F,Rodríguez D

更新日期：2015-06-12 00:00:00

abstract：:Microneedle technology is one of the attractive methods in transdermal drug delivery. However, the clinical applications of this method are limited owing to: complexity in the preparation of multiple coating solutions, drug leakage while inserting the microneedles into the skin and the outer walls of the solid microne...

journal_title：Biointerphases

authors： Vinayakumar KB,Hegde GM,Ramachandra SG,Nayak MM,Dinesh NS,Rajanna K

更新日期：2015-06-08 00:00:00

abstract：:Using infrared and Raman microspectroscopy, the authors examined the interaction of cold atmospheric plasma with the skin's built-in protective cushion, the outermost skin layer stratum corneum. Following a spectroscopic analysis, the authors could identify four prominent chemical alterations caused by plasma treatmen...

journal_title：Biointerphases

authors： Kartaschew K,Mischo M,Baldus S,Bründermann E,Awakowicz P,Havenith M

更新日期：2015-06-06 00:00:00

abstract：:Permanent implants made from titanium are widely used and successfully implemented in medicine to address problems related to orthopedic and oral disorders. However, implants that interact in all cases optimally and durably with bone tissue have yet to be developed. Here, the authors suggest a phospholipids 1-palmitoy...

journal_title：Biointerphases

authors： Golub M,Lott D,Garamus VM,Laipple D,Stoermer M,Watkins EB,Schreyer A,Willumeit-Römer R

更新日期：2015-03-29 00:00:00

abstract：:The precise use of nanoparticles in technological applications requires control over their surface properties. This implies the ability to quantitatively describe, for example, molecular coatings in terms of their thickness, areal mass, or number of molecules. Here, the authors describe two different approaches to the...

journal_title：Biointerphases

authors： Belsey NA,Shard AG,Minelli C

更新日期：2015-03-27 00:00:00

abstract：:Herein, the authors report and review polyelectrolyte complex (PEC) nanoparticles (NPs) loaded with zoledronate (ZOL) and simvastatin and their effects on bone cells. PEC NPs are intended for modification of bone substitute materials. For characterization, they can be solution casted on germanium (Ge) substrates servi...

journal_title：Biointerphases

authors： Müller M,Torger B,Wehrum D,Vehlow D,Urban B,Woltmann B,Hempel U

更新日期：2015-03-23 00:00:00

abstract：:In plants, algae, and cyanobacteria, photosystem 2 (PS2) catalyzes the light driven oxidation of water. The main products of this reaction are protons and molecular oxygen. In vitro, however, it was demonstrated that reactive oxygen species like hydrogen peroxide are obtained as partially reduced side products. The tr...

journal_title：Biointerphases

authors： Vöpel T,Ning Saw E,Hartmann V,Williams R,Müller F,Schuhmann W,Plumeré N,Nowaczyk M,Ebbinghaus S,Rögner M

更新日期：2015-03-22 00:00:00

abstract：:With the advent of novel fabrication technologies, free-standing poly(l-lactic acid) (PLLA) nanosheets have been shown to have enhanced performance over their micro- or macroscale equivalents as tissue engineering and drug delivery constructs. In the present research, the authors investigated the surface degradation b...

journal_title：Biointerphases

authors： Marchany MD,Gardella JA Jr,Kuchera TJ

更新日期：2015-03-20 00:00:00

abstract：:Gold nanoparticles (AuNPs) are good nonviral carriers because of their ease of synthesis and conjugation in biochemistry, and self-assembled monolayers (SAMs) provide a tunable system to change their interfacial properties. Using homogeneously mixed carboxylic acid and amine functional groups, a series of surface pote...

journal_title：Biointerphases

authors： Chang HY,You YW,Liao HY,Shyue JJ

更新日期：2014-12-01 00:00:00

abstract：:The application of magnesium alloys as biomaterials is limited by their poor corrosion behavior. Microarc oxidation (MAO) treatment was used to prepare ceramic coatings on ZK60 magnesium alloys in order to overcome the poor corrosion resistance. The process was conducted at different current densities (3.5 and 9.0 A/d...

journal_title：Biointerphases

authors： You Q,Yu H,Wang H,Pan Y,Chen C

更新日期：2014-09-01 00:00:00

abstract：:The peculiar Cuvierian tubules of sea cucumbers function as a defense mechanism. They thwart attacks by creating a sticky network composed of elongated tubules within which the potential predator is entangled in a matter of seconds and thus immobilized. Cuvierian tubules are typical instantaneous adhesive organs in wh...

journal_title：Biointerphases

authors： Demeuldre M,Chinh Ngo T,Hennebert E,Wattiez R,Leclère P,Flammang P

更新日期：2014-06-01 00:00:00

abstract：:Because dental implant abutments are located at transmucosal sites, their surface should inhibit bacterial accumulation to prevent peri-implantitis. The authors examined the effects of human lactoferrin (LF), an antibacterial protein present in saliva, as an antibacterial coating on the titanium surface and evaluated ...

journal_title：Biointerphases

authors： Nagano-Takebe F,Miyakawa H,Nakazawa F,Endo K

更新日期：2014-06-01 00:00:00

abstract：:Neuronal process growth is guided by extrinsic environmental cues such as extracellular matrix (ECM) proteins. Recent reports have described that the growth cone extension is superior across gradients of the ECM protein laminin compared to growth across uniformly distributed laminin. In this work, the authors have pre...

journal_title：Biointerphases

authors： Zander NE,Beebe TP Jr

更新日期：2014-03-01 00:00:00

abstract：:The limit of detection of advanced immunoassays, biochips and micro/nano biodetection devices is impacted by the non-specific adsorption of target molecules at the sample surface. In this paper, we present a simple and versatile low cost method for generating active surfaces composed of antibodies arrays surrounded by...

journal_title：Biointerphases

authors： Egea AM,Trévisiol E,Vieu C

更新日期：2013-12-01 00:00:00

abstract：:Many studies have examined the effects of surface topography on the settlement behaviour of marine organisms and this article reviews these investigations with more emphasis on the effects of topography scale. It has been observed that macro topographies (1-100 mm) are generally favoured by marine fouling taxa and are...

journal_title：Biointerphases

authors： Myan FW,Walker J,Paramor O

更新日期：2013-12-01 00:00:00

abstract：:Commonly used implants for therapeutic approaches of non-systemically impaired bone do not sufficiently support the healing process of osteoporotic bone. Since strontium (II) has been proven as an effective anti-osteoporotic drug new types of strontium enriched calcium phosphate bone cements were developed. As osteopo...

journal_title：Biointerphases

authors： Kokesch-Himmelreich J,Schumacher M,Rohnke M,Gelinsky M,Janek J

更新日期：2013-12-01 00:00:00

abstract：:Hydrotalcite (HT) and other layered double metal hydroxides are of great interest as gene delivery and timed release drug delivery systems and as enteric vehicles for biologically active molecules that are sensitive to gastric fluids. HT is a naturally occurring double metal hydroxide that can be synthesized as a nano...

journal_title：Biointerphases

authors： Sanderson BA,Sowersby DS,Crosby S,Goss M,Lewis LK,Beall GW

更新日期：2013-12-01 00:00:00

abstract：:Although it is well known that the textural properties of scaffolds play an important role in the process of tissue regeneration, the investigation of such effects remain difficult especially at the micro/nano level. Texture confers the material the additional ability to entrap/concentrate molecules circulating in the...

journal_title：Biointerphases

authors： Espanol M,Casals I,Lamtahri S,Valderas MT,Ginebra MP

更新日期：2012-12-01 00:00:00

abstract：:Inspired by the composition of the native extracellular matrix, biomimetic polyelectrolyte multilayers were assembled from polypeptides and the glycosaminoglycan chondroitin sulfate (CS). To investigate whether peptide conformation imposes an effect on the cell biological functions of osteoblasts, the secondary struct...

journal_title：Biointerphases

authors： Grohmann S,Rothe H,Liefeith K

更新日期：2012-12-01 00:00:00

abstract：:The aim was to compare the protein release from normal human osteoblasts (NHO) cultured on scaffolds with similar morphology but different coatings. Different ceramic coatings; TiO(2), SiO(2) and calcium phosphate (CaP); Ca(9)HPO(4)(PO(4))(5)OH, were applied to porous TiO(2) scaffolds prepared by polymer sponge replic...

journal_title：Biointerphases

authors： Verket A,Tiainen H,Haugen HJ,Lyngstadaas SP,Nilsen O,Reseland JE

更新日期：2012-12-01 00:00:00

abstract：:In the present study, we investigated the hydrothermal treatment of titanium with divalent cation solutions and its effect in promoting the adhesion of gingival epithelial cells and fibroblasts in vitro. Gingival keratinocyte-like Sa3 cells or fibroblastic NIH3T3 cells were cultured for 1 h on experimental titanium pl...

journal_title：Biointerphases

authors： Okawachi H,Ayukawa Y,Atsuta I,Furuhashi A,Sakaguchi M,Yamane K,Koyano K

更新日期：2012-12-01 00:00:00

abstract：:Nanoparticles (NPs) are gaining increasing attention for potential application in medicine; consequently, studying their interaction with cells is of central importance. We found that both ligand arrangement and composition on gold nanoparticles play a crucial role in their cellular internalization. In our previous in...

journal_title：Biointerphases

authors： Carney RP,Carney TM,Mueller M,Stellacci F

更新日期：2012-12-01 00:00:00

abstract：:To image inflammation sites, we developed a novel nanoparticle, hydroxylamine-containing nanoparticle (HANP), which emits an intense electron spin resonance (ESR)-signal triggered by enzymatic oxidation reaction and pH-sensitive self-disintegration. The nanoparticle was prepared from an amphiphilic block copolymer, po...

journal_title：Biointerphases

authors： Yoshitomi T,Nagasaki Y

更新日期：2012-12-01 00:00:00

abstract：:The mechanical properties and responses of cells to external stimuli (including drugs) are closely connected to important phenomena such as cell spreading, motility, activity, and potentially even differentiation. Here, reversible changes in the viscoelastic properties of surface-attached fibroblasts were induced by t...

journal_title：Biointerphases

authors： Tymchenko N,Nilebäck E,Voinova MV,Gold J,Kasemo B,Svedhem S

更新日期：2012-12-01 00:00:00

abstract：:Collecting information at the interface between living cells and artificial substrates is exceedingly difficult. The extracellular matrix (ECM) mediates all cell-substrate interactions, and its ordered, fibrillar constituents are organized with nanometer precision. The proceedings at this interface are highly dynamic ...

journal_title：Biointerphases

authors： Diesner MO,Welle A,Kazanci M,Kaiser P,Spatz J,Koelsch P

更新日期：2011-12-01 00:00:00

abstract：:Gold nanoparticles (AuNPs) functionalized with a short chain amine-terminated alkanethiol (HS-(CH(2))(2)NH(2) or C2 NH(2)-thiol) are prepared via a direct synthesis method and then ligand-exchanged with a long chain amine-terminated alkanethiol (HS-(CH(2))(11)NH(2) or C11 NH(2)-thiol). Transmission electron microscopy...

journal_title：Biointerphases

authors： Techane SD,Gamble LJ,Castner DG

更新日期：2011-09-01 00:00:00

abstract：:Coatings of biomaterials or implants that facilitate biomineralization possess a great potential for applications focused to the replacement, augmentation, and regeneration of bone tissue. Biomimetic approaches utilize biomolecules for either templating or supporting the crystallization process. One of these promising...

journal_title：Biointerphases

authors： Grohmann S,Rothe H,Eisenhuth S,Hoffmann C,Liefeith K

更新日期：2011-06-01 00:00:00

abstract：:Photolithographic techniques have been used to fabricate polymer brush micro- and nanostructures. On exposure to UV light with a wavelength of 244 nm, halogens were selectively removed from films of chloromethylphenyltrichlorosilane and 3-(2-bromoisobutyramido)propyl-triethoxysilane on silicon dioxide. Patterning was ...

journal_title：Biointerphases

authors： Ahmad SA,Leggett GJ,Hucknall A,Chilkoti A

更新日期：2011-03-01 00:00:00

abstract：:The kinetics of adsorption and desorption of two highly asymmetrical model peptides were studied at methyl- and carboxylic acid-terminated alkylthiolate self-assembled monolayer (SAM) surfaces on gold. The model peptides were leucine-lysine (LK), α-helical (LKα14), and β-strand (LKβ15) peptides that have a well-define...

journal_title：Biointerphases

authors： Apte JS,Gamble LJ,Castner DG,Campbell CT

更新日期：2010-12-01 00:00:00

abstract：:In this study, the authors report that sodium citrate can aggregate hexadecyl-trimethyl-ammonium ion(+)-coated gold nanorods (AuNRs), and nucleic acids of different charge and structure properties, i.e., single-stranded DNA (ssDNA), double-stranded DNA (dsDNA), single-stranded peptide nucleic acid (PNA), and PNA-DNA c...

journal_title：Biointerphases

authors： Kanjanawarut R,Su X

更新日期：2010-09-01 00:00:00

abstract：:Friction force microscopy was employed for the tribological investigation of human head hair in two different environments: a dry atmosphere and de-ionized water. The fibers were immobilized by embedding them in indium. The effects of bleaching, conditioning, and immersion in methanolic KOH were quantified in terms of...

journal_title：Biointerphases

authors： Nikogeorgos N,Fletcher IW,Boardman C,Doyle P,Ortuoste N,Leggett GJ

更新日期：2010-06-01 00:00:00

abstract：:The structure, orientation, and formation of amphiphilic alpha-helix model peptide films on fluorocarbon surfaces has been monitored with sum frequency generation (SFG) vibrational spectroscopy, near-edge x-ray absorption fine structure (NEXAFS) spectroscopy, and x-ray photoelectron spectroscopy (XPS). The alpha-helix...

journal_title：Biointerphases

authors： Weidner T,Samuel NT,McCrea K,Gamble LJ,Ward RS,Castner DG

更新日期：2010-03-01 00:00:00